Multiple Myeloma`lı hastalarda ve sağlıklı kişilerde serum İL-6 (İnterleukin-6) seviyelerinin incelenmesi ve multiple myeloma etyolojisine genel bakış
dc.contributor.advisor | Fırat, Dinçer | |
dc.contributor.author | Ercan, Aygün | |
dc.date.accessioned | 2020-12-30T08:26:27Z | |
dc.date.available | 2020-12-30T08:26:27Z | |
dc.date.submitted | 1996 | |
dc.date.issued | 2018-08-06 | |
dc.identifier.uri | https://acikbilim.yok.gov.tr/handle/20.500.12812/498767 | |
dc.description.abstract | IV ÖZET Multiple Myeloma etyolojisinde önemi ve myeloma hücreleri için growth faktör ( hüyüme faktörü) etkisi olan IL-6 ( in terle uk in -6) seviyeleri, bu. hastalarda yüksek ola- larak tesbit edilmektedir. Bizde toplam 16 kişinin (sekiz multiple myeloma hastası, sekiz sağlıklı kişi) serum IL-6 seviyelerini inceledik. IL-6 seviyeleri `human IL-6, R&J) systems /tJSA ` kitleri ile ve ` quantitative sandwich enzyme immunoassay technique ` metodu kullanılarak ölçül müştür. Multiple myelomalı hastalarda sağlam kişilere göre serum IL-6 seviyeleri yüksek çıkmıştır ve Mann.Whitney metoduna göre istatistiksel olarak `bu fark anlamlı ?bulun muştur (u:63, p:0,001). Anahtar kelimeler? Multiple Myeloma, IL-6. | |
dc.description.abstract | ABSTRACT The IL-6 rates which carry importance for the growth factor of myeloma cells have been measured higher Multiple Myeloma these potients. We have examined a total of 16 patient (eight of whom had multiple myeloma disease and eight of whom were healthy people) in whom serum 11-6 rates were investigated. The IL-6 rates have been measured by ` human IL-6 E %- D Systems/ÜSA ` kits and ** quantitative sandwich en2yme immunoasssay technique '. methodo The IL-6 serum rates are encountered highes Multiple Myeloma patients with recpect to the normal persons. Acsording to the ` Mann-Whitney Method `, this difference is istatistically recognised very meaningful (u:63»p:0.001). Key words: Multiple myeloma, IL-6. | en_US |
dc.language | Turkish | |
dc.language.iso | tr | |
dc.rights | info:eu-repo/semantics/embargoedAccess | |
dc.rights | Attribution 4.0 United States | tr_TR |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject | Onkoloji | tr_TR |
dc.subject | Oncology | en_US |
dc.title | Multiple Myeloma`lı hastalarda ve sağlıklı kişilerde serum İL-6 (İnterleukin-6) seviyelerinin incelenmesi ve multiple myeloma etyolojisine genel bakış | |
dc.title.alternative | The Analysis of serum Il-6 (Interleukin-6) levels in patients with multiple myeloma and normal patients and a general look on the etiology of multiple myeloma | |
dc.type | masterThesis | |
dc.date.updated | 2018-08-06 | |
dc.contributor.department | Diğer | |
dc.subject.ytm | Interleukin 6 | |
dc.subject.ytm | Multiple myeloma | |
dc.identifier.yokid | 48647 | |
dc.publisher.institute | Sağlık Bilimleri Enstitüsü | |
dc.publisher.university | HACETTEPE ÜNİVERSİTESİ | |
dc.identifier.thesisid | 48647 | |
dc.description.pages | 170 | |
dc.publisher.discipline | Diğer |