Akut koroner sendrom nedeniyle perkütan koroner girişim yapılan hastalarda biyokimyasal parametreler ve epikardiyal yağ kalınlığı ile kontrast madde nefropatisi arasındaki ilişki

Abstract

Aim: The aim of this study was to investigate whether there is a relationshipbetween contrast induced nephropathy (CIN) and epicardial adipose tissue (EAT)in addition to biochemical parameters in patients undergoing coronaryangiography (CAG) and percutaneous coronary intervention (PCI) due to acutecoronary syndrome (ACS).Methods: Patients who underwent PCI due to ACS between 01/02/2017 and01/09/2017 were also examined cross-sectional and retrospectively. A total of 302patients were included in the study. A possible relationship between CIN withEAT, other echocardiographic parameters and biochemical parameters wasevaluated by statistical analysis.Results: 61 of the patients developed CIN (age: 67.8 ± 12.8 years) and 241 ofthem did not develop CIN (age: 61.5 ± 10.9). EAT, age, hypertension, aorticsclerosis, HbA1c, uric acid, fibrinogen, DM, insulin use, smoking, Mehran score,mitral annuler calcification and creatinine levels on admisson were found to berelated to CIN. Aortic sclerosis, uric acid and HbA1c were independent predictorof the development of CIN.Conclusions: In patients who underwent PCI due to ACS, an increase in theamount of EAT was associated with the risk of developing CIN. Aortic sclerosis,uric acid and HbA1c were independent risk factors for CIN.Keywords: Acute coronary syndrome, epicardial adipose tissue, contrast inducednephropathy

Aim: The aim of this study was to investigate whether there is a relationshipbetween contrast induced nephropathy (CIN) and epicardial adipose tissue (EAT)in addition to biochemical parameters in patients undergoing coronaryangiography (CAG) and percutaneous coronary intervention (PCI) due to acutecoronary syndrome (ACS).Methods: Patients who underwent PCI due to ACS between 01/02/2017 and01/09/2017 were also examined cross-sectional and retrospectively. A total of 302patients were included in the study. A possible relationship between CIN withEAT, other echocardiographic parameters and biochemical parameters wasevaluated by statistical analysis.Results: 61 of the patients developed CIN (age: 67.8 ± 12.8 years) and 241 ofthem did not develop CIN (age: 61.5 ± 10.9). EAT, age, hypertension, aorticsclerosis, HbA1c, uric acid, fibrinogen, DM, insulin use, smoking, Mehran score,mitral annuler calcification and creatinine levels on admisson were found to berelated to CIN. Aortic sclerosis, uric acid and HbA1c were independent predictorof the development of CIN.Conclusions: In patients who underwent PCI due to ACS, an increase in theamount of EAT was associated with the risk of developing CIN. Aortic sclerosis,uric acid and HbA1c were independent risk factors for CIN.Keywords: Acute coronary syndrome, epicardial adipose tissue, contrast inducednephropathy.