Bazı açilamidrazon ve 1,2,4-triazol türevlerinin susuz ortamda pKa değerlerinin tayini

Abstract

ÖZET Bu çalışmada, açilamidrazon türevleri olan N-(4-hidroksibenzoil)- asetamidrazon, N-izonikotinoilasetamidrazon, N-izonikotinoilbenzamidrazon ve 1,2,4-triazol türevleri olan 3-metil-5-(4-hidroksifenil)-l,2,4-triazol, 3-metil-5-(4- piridil)- 1,2,4-triazol, 3 -metil-5-siyanometil- 1,2,4-triazol, 3 -fenil-5-(4-piridil)- 1,2,4-triazol, 3-fenil-5-(4-hidroksibenzoil)-l,2,4-triazol bileşiklerin susuz ortamda potansimetrik yöntemle yan nötralizasyon sabitleri (HNP) tayin edilmiş ve karşılık gelen asitlik sabitleri (pKa) bulunmuştur. Anahtar Kelimeler: Açilamidrazon, 1,2,4-triazol, asitlik sabiti, yarı nötralizasyon noktası. III

SUMMARY In this study, by making use of some acylamidrazones and some 1,2,4- triazol derivatives such as N1-(4-hydroxybenzoyl)-acetamidrazon, N1- isonicotinoylacetamidrazon, N'-isonicotinoylbenzamidrazon, 3-methyl-5-(4- hydroxyphenyl)-l,2,4-triazole, 3-methyl-5-(4-pyridyl)-l,2,4-triazole, 3-methyl-5- cyanomethyl-l,2,4-triazole, 3-phenyl-5-(4-pyridyl)-l,2,4-triazole and 3-phenyl-5- (4-hydroxybenzoyl)-l,2,4-triazoles half notralization point values (HNP) were determined by main of potantiometric method in non-aquaous media and acidity constants (pKa) were found. Key Words: Acylamidrazone, 1,2,4-triazole, acidity constant, half notralization point. IV