Analjin (Novaljin) içeren farmasötik preparatlardaki etken maddelerin spektrofotometrik yöntemlerle miktar tayinleri

Abstract

282 226,1 nm for analgirte and at 238,6 nm for aspirin. Although the decreasing of the slit width and AX, values we couldn't achieved the determination of carisoprodol in this ternary mixture and the method has been applied to a dragee preparation containing this mixture for the determination of analgine and aspirin. In this ternary mixture, the determination of the analgine has not been made selectively by pyrocatechol method by the fact that aspirin also produced same reaction with pyrocatechol as with analgine.281 derivative absorbances at 290,0 nm in the first derivative spectrum (AX = 2 nm) of the same chloroform layer for analgine. This method has been developed by us and applied to an injection preparation containing this mixture. The amount of the analgine has been found by using pyrocatechol method by its selectivity for analgine in the presence of lidocaine.HCl and the results has been compared with those obtained in the methods mentioned above. In analgine - adamon mixture : The simultaneous determination of analgine and adamon have been realized by measuring the derivative absorbances at 291,8 nm for analgine and 234,8 nm for adamon in the first derivative spectrum of the solution of the mixture in 0,1 N HCI. The method has been succesfully applied to a injection preparation containing this binary mixture. The simultaneous determination of analgine and adamon were made in their mixture by reading the derivative absorbances in the first derivative spectrum of the chloroform layer at 600,0 nm for analgine and at 310,5 nm for adamon after treating the mixture with thymol blue at pH = 3,6 and then extraction of the ion-pair (1:1) formed into chloroform. This method was developed by us and the method has been applied to an injection preparation containing this mixture. The amount of the analgine has been found by using pyrocatechol method by its selectivity for analgine in the presence of lidocaine.HCl and the results has been compared with those obtained in the methods explained above. In analgine - aspirin - carisoprodole mixture : The simultaneous determination of the analgine and aspirin in this mixture have been realized by reading the derivative absorbances in the first derivative spectrum of the solution of the mixture in methanol (AX = 2 nm) at282 226,1 nm for analgirte and at 238,6 nm for aspirin. Although the decreasing of the slit width and AX, values we couldn't achieved the determination of carisoprodol in this ternary mixture and the method has been applied to a dragee preparation containing this mixture for the determination of analgine and aspirin. In this ternary mixture, the determination of the analgine has not been made selectively by pyrocatechol method by the fact that aspirin also produced same reaction with pyrocatechol as with analgine.281 derivative absorbances at 290,0 nm in the first derivative spectrum (AX = 2 nm) of the same chloroform layer for analgine. This method has been developed by us and applied to an injection preparation containing this mixture. The amount of the analgine has been found by using pyrocatechol method by its selectivity for analgine in the presence of lidocaine.HCl and the results has been compared with those obtained in the methods mentioned above. In analgine - adamon mixture : The simultaneous determination of analgine and adamon have been realized by measuring the derivative absorbances at 291,8 nm for analgine and 234,8 nm for adamon in the first derivative spectrum of the solution of the mixture in 0,1 N HCI. The method has been succesfully applied to a injection preparation containing this binary mixture. The simultaneous determination of analgine and adamon were made in their mixture by reading the derivative absorbances in the first derivative spectrum of the chloroform layer at 600,0 nm for analgine and at 310,5 nm for adamon after treating the mixture with thymol blue at pH = 3,6 and then extraction of the ion-pair (1:1) formed into chloroform. This method was developed by us and the method has been applied to an injection preparation containing this mixture. The amount of the analgine has been found by using pyrocatechol method by its selectivity for analgine in the presence of lidocaine.HCl and the results has been compared with those obtained in the methods explained above. In analgine - aspirin - carisoprodole mixture : The simultaneous determination of the analgine and aspirin in this mixture have been realized by reading the derivative absorbances in the first derivative spectrum of the solution of the mixture in methanol (AX = 2 nm) at282 226,1 nm for analgirte and at 238,6 nm for aspirin. Although the decreasing of the slit width and AX, values we couldn't achieved the determination of carisoprodol in this ternary mixture and the method has been applied to a dragee preparation containing this mixture for the determination of analgine and aspirin. In this ternary mixture, the determination of the analgine has not been made selectively by pyrocatechol method by the fact that aspirin also produced same reaction with pyrocatechol as with analgine.