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dc.contributor.advisorNecefoğlu, Hacali
dc.contributor.authorAydoğdu, Ömer
dc.date.accessioned2023-09-22T11:46:50Z
dc.date.available2023-09-22T11:46:50Z
dc.date.submitted2023-02-27
dc.date.issued2022
dc.identifier.urihttps://acikbilim.yok.gov.tr/handle/20.500.12812/735999
dc.description.abstractTez çalışması kapsamında Nikotinikhidrazid ve türevleri (Pikolinikhidrazid, İzonikotinikhidrazid) ve Piridinkarboksialdehitler (Pikolinik aldehit, Nikotinik aldehit, İzonikotinik aldehit) kullanılarak yedi Schiff bazı bileşiği sentezlendi: C12H10N4O – N'-(Piridin-2-ilmetilen)pikolinohidrazid (I), C12H10N4O – N'-(Piridin-3-ilmetilen) pikolinohidrazid (II), C12H10N4O – N'-(Piridin-4-ilmetilen)pikolinohidrazid (III), C12H10N4O·2(H2O) – N'-(Piridin-2-ilmetilen)nikotinohidraziddihidrat (IV), C12H10N4O – N'-(Piridin-2-ilmetilen)izonikotinohidrazid (V), C12H10N4O – N'-(Piridin-3-ilmetilen) izonikotinohidrazid (VI), C12H10N4O – N'-(Piridin-4-ilmetilen)izonikotinohidrazid (VII). I, III, IV, V ve VI numaralı Schiff bazı bileşiklerinden Zn(II) ve Cu(II) kompleksleri sentezlenmiştir: C12H9Cl2N4OZn – [N'-(pikolinilpiridin-2-karbohidrazonat)çinko(II)diklorür] (VIII),C12H9ClCuN4O – Catena-Poli[N'-(pikolinilpiridin-3-karbohidrazonat)bakır(II) mono klorür] (IX), C24H20Cl2N8O2Zn·2(H2O) – Bis-[N'-(Piridin-4-ilmetilen)pikolinohidrazid]çinko(II) diklorürdihidrat (X), C12H11Cl3N4OZn – [N'-(Piridin-2-ilmetilen)izonikotinohidrazid] trikoloroçinkoat (XI), C12H11Cl3N4OZn – [N'-(Piridin-3-ilmetilen)izonikotinohidrazid] trikoloroçinkoat (XII). Schiff bazı bileşikleri ve komplekslerin yapıları elemental analiz, FT-IR spektroskopisi, UV-Vis spektrofotometresi, 1H-NMR ve 13C-NMR spektroskopisi ve tek kristal X-ışını diffraktometresi yöntemleri kullanılarak aydınlatılmıştır. Ayrıca Schiff bazı bileşiklerinin ve komplekslerin antibakteriyel aktiviteleri agar kuyucuk difüzyon yöntemiyle incelenmiştir.
dc.description.abstractWithin the scope of the thesis study, seven Schiff base compounds were synthesized with Nicotinichydrazide and its derivatives (picolinichydrazide, isonicotinichydrazide) and pyridinecarboxyaldehydes (picolinic aldehyde, Nicotinic aldehyde, Isonicotinic aldehyde): C12H10N4O – N'-(Pyridin-2-ylmethylene)picolinohydrazide(I), C12H10N4O – N'-(Pyridin-3-ylmethylene)picolinohydrazide (II), C12H10N4O – N'- (Pyridin-4-ylmethylene)picolinohydrazide(III),C12H10N4O·2(H2O) – N'- (Pyridin-2-ylmethylene)nicotinohydrazidedihydrate (IV), C12H10N4O – N'-(Pyridin-2-ylmethylene)isonicotinohydrazide (V), C12H10N4O – N'-(Pyridin-3-ylmethylene)isonicotinohydrazide(VI), C12H10N4O – N'-(Pyridin-4-ylmethylene)isonicotinohydrazide(VII).Zn(II) and Cu(II) complexes were synthesized from Schiff base compound I, III, IV, V and VI: C12H9Cl2N4OZn – [N'-(picolinylpyridine-2-carbohydrazonate)zinc(II)dichloride] (VIII), C12H9ClCuN4O – Catena-Poly[N'-(picolinylpyridine-3-carbohydrazonate) copper(II) monochloride] (IX), C24H20Cl2N8O2Zn·2(H2O) – Bis-[N'-(Pyridin-4-ylmethylene)picolinohydrazide]zinc(II) dichloridedihydrate (X), C12H11Cl3N4OZn – [N'-(Pyridin-2-ylmethylene)isonicotinohydrazide]trichlorozincoate (XI), C12H11Cl3N4OZn – [N'-(Pyridin-3-ylmethylene)isonicotinohydrazide]trichlorozincoate (XII).The structures of Schiff base compounds and complexes were elucidated using elemental analysis, FT-IR spectroscopy, UV-Vis spectrophotometer, 1H-NMR and 13C-NMR spectroscopy, and single-crystal X-ray diffractometry methods. In addition, antibacterial activities of Schiff base compounds and complexes were investigated by the agar well diffusion method. Formulas of synthesized Schiff base compounds and complexes were determined.en_US
dc.languageTurkish
dc.language.isotr
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAttribution 4.0 United Statestr_TR
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectKimyatr_TR
dc.subjectChemistryen_US
dc.titleNikotinik hidrazid türevleri esasında Schiff bazlar ve metal komplekslerinin sentezi, fiziksel, biyolojik ve yapısal özellikleri
dc.title.alternativeSynthesis, physical, biological and structural properties of Schiff bases and metal complexes on the basis of nicotinic hydrazide derivatives
dc.typedoctoralThesis
dc.date.updated2023-02-27
dc.contributor.departmentKimya Ana Bilim Dalı
dc.subject.ytmNiacin
dc.subject.ytmPyridine adsorption
dc.subject.ytmSchiff bases
dc.subject.ytmSupramolecular chemistry
dc.subject.ytmX ray diffraction
dc.identifier.yokid10330777
dc.publisher.instituteFen Bilimleri Enstitüsü
dc.publisher.universityKAFKAS ÜNİVERSİTESİ
dc.identifier.thesisid710289
dc.description.pages197
dc.publisher.disciplineDiğer


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