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dc.contributor.advisorDilek, Osman Nuri
dc.contributor.authorŞan, Osman
dc.date.accessioned2021-05-06T11:57:00Z
dc.date.available2021-05-06T11:57:00Z
dc.date.submitted2006
dc.date.issued2018-08-06
dc.identifier.urihttps://acikbilim.yok.gov.tr/handle/20.500.12812/585911
dc.description.abstractVII. ÖZET Amaç: Bu çalışmanğın amacı değişik basınçlarda ve peritonitin eşlik ettiği durumlarda kolon primer anastomozunun güvenililirliğini değerlendirmektir. Gereç ve yöntem: Altmış adet erişkin, erkeklerden izole edilmiş, 200-220 g ağırlığında dişi Spraque Dawley cinsi ratlar çalışmaya. Ratlar randomize olarak 6 gruba ayrıldılar. Gruplar; kontrol, 15 mmHg, 25 mmHg, peritonit, peritonit+15mmHg, peritonit+25 mmHg şeklinde oluşturuldu. Basınç gruplarına 60 dakika intrabdominal basınç uygulandı ve ratlar monitörize edildi. Daha sonra her bir gruba sağ kolondan bir cm rezeksiyon ve anastomoz yapıldı. Postoperatif 7. gün anastomoz yapılan kolon segmenti çıkarılarak patlama basınçları ölçüldükten sonra histopatolojik olarak incelendi. Bulgular: APB kontrol grubu ile 15mmHg grubu arasında istatistiksel olarak anlamlı bir fark yoktu. Fakat 25 mmHg grubu ile kontrol ve 15mmHg grupları arasında istatistiksel olarak anlamlı fark vardı (p<0.05). Peritonit grupları arasında istatistiksel olarak fark yoktu (P>0.05). Kontrol grubu ile peritonit+ISmmHg ve peritonit+25mmHg arasında istatistiksel olarak anlamlı fark vardı (p< 0.05). 15 mmHg ve peritonit+15mmHg arasında istatistiksel olarak anlamlı fark vardı (p< 0.05). Sonuç: Abdominal kompartman sendromunda 15 mmHg' ya kadar olan intraabdominal basınç artışlarında eğer peritonit yoksa primer kolon anastomozu yapılabilir. Fakat intraabdominal basınç 25 mmHg üzerine çıktığında ve peritonit mevcudiyetinde primer kolon anastomozu güvenli görünmemektedir. 44
dc.description.abstractVIII. SUMMARY THE EFFECT OF ABDOMINAL COMPARTMENT SYNDROME WITH DIFFERENT PRESSURE AND PERITONITIS TO THE COLON ANASTOMOSES Aim: The purpose of this study is to determine the safety of primer anastomoses of colon in different abdominal pressures and in cases with peritonitis. Materials and Methods: Sixty female bred isolated Sprapue Dawley rats that weighted 200-250 grams were included in the study. Rats were randomly divided in to six groups. Groups were designed as follows: control group, group with 15 mmHg pressure, group with 25 mmHg pressure, group with peritonitis, group with peritonitis and 15mmHg pressure and group with peritonitis and 25 mmHg pressure. Intraabdominal pressure was applied for sixty minutes in pressure groups and rats were monitorised. Afterwards, one cm resection and anastomoses were performed to each group in right colon. The segment of anastomosed colon excised and anastomose bursting pressure (ABP) was measured and colon segment was sampled for histopathologic examination at the end of study. Results: There was no statistically significant difference between control group and group with 15 mmHg pressure in ACS. But there was statistically significant difference between control group, group with 15 mmHg pressure and group with 25 mmHg pressure (p< 0.05). There was no statistically significant difference between group of peritonitis. There was statistically significant difference between control group and group with peritonitis and 15 mmHg pressure (p< 0.05). There was statistically significant difference between control group and group with peritonitis and 25 mmHg pressure (p< 0.05). There was statistically significant difference between group withl5 mmHg pressure and group with peritonitis and 15 mmHg pressure (p< 0.05). In conclusion, primary anastomoses of colon could be performed in ACS with 15 mmHg or less pressures, if peritonitis is not observed. But if intraabdominal pressure is 25 mmHg or higher and if peritonitis is observed, primary anastomoses of colon could not be accepted as safe prosedüre. 45en_US
dc.languageTurkish
dc.language.isotr
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.rightsAttribution 4.0 United Statestr_TR
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectGenel Cerrahitr_TR
dc.subjectGeneral Surgeryen_US
dc.titleAbdominal kompartman sendromunun değişik basınç ve peritonit durumunda kolon anastomozu üzerine etkisi
dc.title.alternativeThe effect of abdominal compartment syndrome with different pressure and pertonitis to the colon anastomoses
dc.typedoctoralThesis
dc.date.updated2018-08-06
dc.contributor.departmentGenel Cerrahi Ana Bilim Dalı
dc.identifier.yokid194154
dc.publisher.instituteTıp Fakültesi
dc.publisher.universityAFYON KOCATEPE ÜNİVERSİTESİ
dc.type.submedicineThesis
dc.identifier.thesisid171689
dc.description.pages57
dc.publisher.disciplineDiğer


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