Parkinson hastalığının tedavisinde kullanılan rotigotin, rasagilin ve ladotigil ilaçlarının bazı türevlerinin sentezi
dc.contributor.advisor | Göksu, Süleyman | |
dc.contributor.author | Polat, Leyla | |
dc.date.accessioned | 2020-12-03T13:24:39Z | |
dc.date.available | 2020-12-03T13:24:39Z | |
dc.date.submitted | 2011 | |
dc.date.issued | 2018-08-06 | |
dc.identifier.uri | https://acikbilim.yok.gov.tr/handle/20.500.12812/49969 | |
dc.description.abstract | Rotigotin, Rasagilin ve Ladotigilin merkezi sinir sistemindeki bozuklukların tedavisinde kullanılmaktadır.Bu yüzden bu tez kapsamında, rotigotin, rasagilin ve ladostigile benzer 7,8-dimetoksi-1,2,3,4-tetrahidronaftalin-2-amin, 4,5-dimetoksi-2,3-dihidro-indan-2-amin, 7,8-dimetoksi-1,2,3,4-tetrahidronaftalin-1-amin, 6,7-dimetoksi-2,3-dihidro-indan-1-amin, ve 5,6-dimetoksi-2,3-dihidro-indan-1-amin sentezi uygun çıkış bileşiklerinden çıkılarak sentezlendi. | |
dc.description.abstract | Rotigotine, Rasagiline and Ladostigile are using for threating CNS-related disorders. Therefore in the present thesis rotigotine, rasagiline and ladostigile like 7,8-dimethoxy-1,2,3,4-tetrahydronaphthalene-2-amine, 4,5-dimethoxy-2,3-dihydro-indene-2-amine, 7,8-dimethoxy-1,2,3,4-tetrahydronaphthalene-1-amine, 6,7-dimethoxy-2,3-dihydro-indene-1-amine and 5,6-dimethoxy-2,3-dihydro-indene-1-amine were synthesized from convenient starting compounds. | en_US |
dc.language | Turkish | |
dc.language.iso | tr | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.rights | Attribution 4.0 United States | tr_TR |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject | Kimya | tr_TR |
dc.subject | Chemistry | en_US |
dc.title | Parkinson hastalığının tedavisinde kullanılan rotigotin, rasagilin ve ladotigil ilaçlarının bazı türevlerinin sentezi | |
dc.title.alternative | Synthesis of some derivatives of rotigotine, rasagiline and ladostigile drugs used in the threatment of parkinson's | |
dc.type | masterThesis | |
dc.date.updated | 2018-08-06 | |
dc.contributor.department | Kimya Anabilim Dalı | |
dc.identifier.yokid | 413820 | |
dc.publisher.institute | Fen Bilimleri Enstitüsü | |
dc.publisher.university | ATATÜRK ÜNİVERSİTESİ | |
dc.identifier.thesisid | 299793 | |
dc.description.pages | 101 | |
dc.publisher.discipline | Diğer |