dc.contributor.advisor | Akkuş, İdris | |
dc.contributor.author | Kaleli, Süleyman | |
dc.date.accessioned | 2020-12-29T16:36:14Z | |
dc.date.available | 2020-12-29T16:36:14Z | |
dc.date.submitted | 1992 | |
dc.date.issued | 2018-08-06 | |
dc.identifier.uri | https://acikbilim.yok.gov.tr/handle/20.500.12812/457242 | |
dc.description.abstract | 44 7. ÖZET Sigara içen sağlıklı kişilerde, koroner kalp hastalarında ve sigara içmeyen sağlıklı kontrol grubunda serum Apolipoprotein Ar (Apo Ar), Apolipoprotein B (ApoB), Total kolesterol (TC), HDL -kolesterol (HDL-C), Trigliserid <TG> fLDL -kolesterol (LDL-C), Fosfolipid (PL) ve Total Lipid seviyeleri tayin edildi. Sonuçlar aşağı daki şekildedir: 1- Sigara içmeyen sağlıklı kişilerde referans değer lerimiz; Apo Ax 203» 42 ± 64,47, Apo B 110,68 ± 40,34, TC 174,58 + 29,44, HDL-C 57,48 ± 8,65, TG 107,9 ± 36,85, LDL - C 121,35 ± 27,68, Fosfolipid 206,84 ± 27,78 ve Total lipid 574,32 ± 97,66 mg/dl, 2- Sigara içenlerde ; Apo Ax 131,47 ± 41,63, Apo E 130,12 * 57,26, TC 201,16 ± 31,08, HDL-C 42,78 * 6,09, TG 147,68 ± 72,89, LDL-C 155,88 ± 27, 78, Fosfolipid 204,39 + 39,86 ve Total lipid 648 ± 127,21 mg/dl, 3- Koroner Kalp Hastalarında ; Apo At 113,9 ± 45,6^, Apo B 167,3 + 62, 22, TC 221,45 ± 39,11, HDL-C 38,8 ± 7,89, TG 178,07 ± 90,14, LDL-C 173,79 ± 37,77, Fosfo lipid 202,97 ± 47,18 ve Total lipid 712,14 ± 165,57 mg/dl olarak bulunmuştur. Sigara içen gruba aid Apo Aı ve HDL-C düzeyleri kontrol grubuna göre istatistiki açıdan önemli derecede düşük, Total kolesterol, trigliserid, LDL-C ve Total lipid değerleri önemli oranda yüksek bulundu. Apo B ve fosfo lipid değerleri arasında önemli bir fark bulunamadı.45 Koroner Kalp Hastalarına aid Apo Ax ve HDL-C düzeyleri kontrol grubuna göre önemli oranda düşük, Apo B, TC, TG, LDL-C ve Total lipid düzeyleri yüksek bulunmuştur. Fosfolipid değerleri arasında önemli bir fark bulunamadı. Koroner Kalp Hastaları ile sigara içen gruba aid parametreler arasında herhangi bir fark bulunamadı. | |
dc.description.abstract | 46 SUMMARY SERUM APO Ai, APO B AND VARIOUS LIPID PARAMETERS OF SMOKING AND NON-SMOKING HEALTY SUBJECTS AND PATIENTS WITH CORONARY HEART DISEASE. Serum Apo A*, Apo B and various lipid parameters of smoking and non-smoking healty subjects ans patients with coronary heart disease were determined. The results are as follows: 1- Non-smoking healty subjects : Apo A* 203, 42 ± 64,47, Apo B 110,68 ± 40,34, Total Cholesterol 174,58 ± 29, 44, HDL -Cholesterol 57,48 ± 8,65, Triglyceride 107,9 ± 36,85, LDL - Cholesterol 121,35 ± 27,68, phospholipid 206,84 + 27,78 and total lipid 574,32 ± 97,66 mg/dl, 2- Cigarette smoking subjects: Apo Ax 131,47 ± 41,63, Apo B 130,12 ± 57,26, Total Cholesterol 201,16 ± 31, 08, HDL -Cholesterol 42,78 ± 6,09, Triglyceride 147,68 ± 72,89, LDL - Cholesterol 155,88 + 27,78, phospholipid 204,39 ± 39,86 and total lipid 648 ± 127,21 mg/dl, 3- Patients with coronary heart disease: Apo hx 113,9 ± 45,64, Apo B 167,3 ± 62,22, Total Cholesterol 221,45 ± 39,11, HDL -Cholesterol 38,8 ± 7,89, Triglyceride 178,07 ± 90,14, LDL - Cholesterol 173,79 ± 37,77, phospholipid 202,97 ± 47,18 and total lipid 712,14 ± 165,57 mg/dl.47 RDL-cholesterol and Apo &i levels of smoking subjects and patients with coronary disease were signify cantly ( p<0,001 ) lower, while total cholesterol, triglyceride, LDL-cholesterol and total lipid values were higher than those of control subjects. There was no difference between Apo B and phos pholipid levels of all the three groups. Also, there was no difference between all parameters of patients with coronary heart disease and smoking subjects. | en_US |
dc.language | Turkish | |
dc.language.iso | tr | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.rights | Attribution 4.0 United States | tr_TR |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.subject | Biyokimya | tr_TR |
dc.subject | Biochemistry | en_US |
dc.title | Sigara içen ve içmeyen sağlıklı kişilerle koroner kalp hastalarında apolipoprotein A1, apolipoprotein B ve bazı lipid parametrelerinin karşılaştırılması | |
dc.title.alternative | Serum APO A1, APO B and various lipid parameters of smoking and non-smoking healty subjects and patients with coronary heart disease | |
dc.type | masterThesis | |
dc.date.updated | 2018-08-06 | |
dc.contributor.department | Biyokimya Anabilim Dalı | |
dc.subject.ytm | Apolipoprotein A I | |
dc.subject.ytm | Apolipoproteins B | |
dc.subject.ytm | Healthy people | |
dc.subject.ytm | Heart diseases | |
dc.subject.ytm | Smoking | |
dc.identifier.yokid | 24516 | |
dc.publisher.institute | Sağlık Bilimleri Enstitüsü | |
dc.publisher.university | SELÇUK ÜNİVERSİTESİ | |
dc.identifier.thesisid | 24516 | |
dc.description.pages | 61 | |
dc.publisher.discipline | Diğer | |