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dc.contributor.advisorAkkuş, İdris
dc.contributor.authorKaleli, Süleyman
dc.date.accessioned2020-12-29T16:36:14Z
dc.date.available2020-12-29T16:36:14Z
dc.date.submitted1992
dc.date.issued2018-08-06
dc.identifier.urihttps://acikbilim.yok.gov.tr/handle/20.500.12812/457242
dc.description.abstract44 7. ÖZET Sigara içen sağlıklı kişilerde, koroner kalp hastalarında ve sigara içmeyen sağlıklı kontrol grubunda serum Apolipoprotein Ar (Apo Ar), Apolipoprotein B (ApoB), Total kolesterol (TC), HDL -kolesterol (HDL-C), Trigliserid <TG> fLDL -kolesterol (LDL-C), Fosfolipid (PL) ve Total Lipid seviyeleri tayin edildi. Sonuçlar aşağı daki şekildedir: 1- Sigara içmeyen sağlıklı kişilerde referans değer lerimiz; Apo Ax 203» 42 ± 64,47, Apo B 110,68 ± 40,34, TC 174,58 + 29,44, HDL-C 57,48 ± 8,65, TG 107,9 ± 36,85, LDL - C 121,35 ± 27,68, Fosfolipid 206,84 ± 27,78 ve Total lipid 574,32 ± 97,66 mg/dl, 2- Sigara içenlerde ; Apo Ax 131,47 ± 41,63, Apo E 130,12 * 57,26, TC 201,16 ± 31,08, HDL-C 42,78 * 6,09, TG 147,68 ± 72,89, LDL-C 155,88 ± 27, 78, Fosfolipid 204,39 + 39,86 ve Total lipid 648 ± 127,21 mg/dl, 3- Koroner Kalp Hastalarında ; Apo At 113,9 ± 45,6^, Apo B 167,3 + 62, 22, TC 221,45 ± 39,11, HDL-C 38,8 ± 7,89, TG 178,07 ± 90,14, LDL-C 173,79 ± 37,77, Fosfo lipid 202,97 ± 47,18 ve Total lipid 712,14 ± 165,57 mg/dl olarak bulunmuştur. Sigara içen gruba aid Apo Aı ve HDL-C düzeyleri kontrol grubuna göre istatistiki açıdan önemli derecede düşük, Total kolesterol, trigliserid, LDL-C ve Total lipid değerleri önemli oranda yüksek bulundu. Apo B ve fosfo lipid değerleri arasında önemli bir fark bulunamadı.45 Koroner Kalp Hastalarına aid Apo Ax ve HDL-C düzeyleri kontrol grubuna göre önemli oranda düşük, Apo B, TC, TG, LDL-C ve Total lipid düzeyleri yüksek bulunmuştur. Fosfolipid değerleri arasında önemli bir fark bulunamadı. Koroner Kalp Hastaları ile sigara içen gruba aid parametreler arasında herhangi bir fark bulunamadı.
dc.description.abstract46 SUMMARY SERUM APO Ai, APO B AND VARIOUS LIPID PARAMETERS OF SMOKING AND NON-SMOKING HEALTY SUBJECTS AND PATIENTS WITH CORONARY HEART DISEASE. Serum Apo A*, Apo B and various lipid parameters of smoking and non-smoking healty subjects ans patients with coronary heart disease were determined. The results are as follows: 1- Non-smoking healty subjects : Apo A* 203, 42 ± 64,47, Apo B 110,68 ± 40,34, Total Cholesterol 174,58 ± 29, 44, HDL -Cholesterol 57,48 ± 8,65, Triglyceride 107,9 ± 36,85, LDL - Cholesterol 121,35 ± 27,68, phospholipid 206,84 + 27,78 and total lipid 574,32 ± 97,66 mg/dl, 2- Cigarette smoking subjects: Apo Ax 131,47 ± 41,63, Apo B 130,12 ± 57,26, Total Cholesterol 201,16 ± 31, 08, HDL -Cholesterol 42,78 ± 6,09, Triglyceride 147,68 ± 72,89, LDL - Cholesterol 155,88 + 27,78, phospholipid 204,39 ± 39,86 and total lipid 648 ± 127,21 mg/dl, 3- Patients with coronary heart disease: Apo hx 113,9 ± 45,64, Apo B 167,3 ± 62,22, Total Cholesterol 221,45 ± 39,11, HDL -Cholesterol 38,8 ± 7,89, Triglyceride 178,07 ± 90,14, LDL - Cholesterol 173,79 ± 37,77, phospholipid 202,97 ± 47,18 and total lipid 712,14 ± 165,57 mg/dl.47 RDL-cholesterol and Apo &i levels of smoking subjects and patients with coronary disease were signify cantly ( p<0,001 ) lower, while total cholesterol, triglyceride, LDL-cholesterol and total lipid values were higher than those of control subjects. There was no difference between Apo B and phos pholipid levels of all the three groups. Also, there was no difference between all parameters of patients with coronary heart disease and smoking subjects.en_US
dc.languageTurkish
dc.language.isotr
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAttribution 4.0 United Statestr_TR
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectBiyokimyatr_TR
dc.subjectBiochemistryen_US
dc.titleSigara içen ve içmeyen sağlıklı kişilerle koroner kalp hastalarında apolipoprotein A1, apolipoprotein B ve bazı lipid parametrelerinin karşılaştırılması
dc.title.alternativeSerum APO A1, APO B and various lipid parameters of smoking and non-smoking healty subjects and patients with coronary heart disease
dc.typemasterThesis
dc.date.updated2018-08-06
dc.contributor.departmentBiyokimya Anabilim Dalı
dc.subject.ytmApolipoprotein A I
dc.subject.ytmApolipoproteins B
dc.subject.ytmHealthy people
dc.subject.ytmHeart diseases
dc.subject.ytmSmoking
dc.identifier.yokid24516
dc.publisher.instituteSağlık Bilimleri Enstitüsü
dc.publisher.universitySELÇUK ÜNİVERSİTESİ
dc.identifier.thesisid24516
dc.description.pages61
dc.publisher.disciplineDiğer


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