Show simple item record

dc.contributor.advisorBüyükbaş, Sadık
dc.contributor.authorGökçen, Mürsel
dc.date.accessioned2020-12-29T16:35:58Z
dc.date.available2020-12-29T16:35:58Z
dc.date.submitted1993
dc.date.issued2018-08-06
dc.identifier.urihttps://acikbilim.yok.gov.tr/handle/20.500.12812/457188
dc.description.abstract39 ÖZET Yaşlan 20-40 arasında olan 54 erkek, 36 kadın Toplam 90 kişiden; 30 zayıf (BMI<20). 30 normal kilolu (BMI=21-26) ve 30 şişman (BMI>25) kişinin, plazmalarında glukoz. bazal insulin, total kolesterol.trigliserit, fosfolipid, HDL- kolesterolLDL kolesterol LDL-kol / HDL-kol oranı PCHE ve EACHE düzeyleri tayin edildi. Zayıf (BMTsı<20) kişilere ait değerler şu şekildedir. Glukoz Bazal Insulin : Total kolesterol : Trigliserit Fosfolipit : HDL-Kolesterol : LDL-kolesterol : LDL-kol/HDL-kol : PCHE : EACHE Normal kilolu (BMTsı 21-25) Glukoz Bazal Insulin : Total kolesterol : Trigiliserit : Fosfolipit HDL-Kolesterol LDL-kolesterol LDL-kol/HDL-kol PCHE EACHE40 Şişman (BMTsı >25 ) kişilere ait değerler şu şekildedir Glukoz Bazal rnsülin Total kolesterol Trigliserit Fosfolipit HDL-Kolesterol LDL-kolesterol LDL-kol/HDL-kol PCHE EACHE 100.2 ± 31.6mg/dl 28.7 ± 11.1 uIU/ml 198.0 ± 39.9mg/dl 147.1 ± 54.8mg/dl 224.1 ± 37.3mg/dl 39.7 ± 9.2 mg/dl 124 ± 33.9 mg/dl 3.36 ± 1.02 mg/dl 8.55 ± 1.07 Ü/L 7377 ± 1428 Ü/L Zayıf grub ile normal kilolu grub karşılaştınldıârnda.Trigliserid (p< 0.01), LDL-Kolesterol (p< 0.01), PACHE (p< 0.001) değerlerinin Zayii kişilerde düşüklüğü, anlamlı bulunmuştur. Şişman grubun Zayıf grub ile karşılaştrnldıgında Trigliserid (p < 0.001), LDL- Kolesterol (p < 0.001) ve PCHE (p < 0.001 ) değerleri zayıf grup da düşükken; HDL- Kolesterol (p < 0.01), EACHE (p< 0.001) yüksekliği anlamlı bulunmuştur Şişman grubun.norrnal kilolu grub ile karşüaştrnldıâmda Trigliserid (p < 0.01). LDL-Kolesterol (p < 0.01), PACHE (p < 0.001) değerleri düşük; EACHE (p < 0.001) yüksek bulunmuştur. Zayıf, Normal kilolu ve Şişman gruplanmızın korelasyon testlerinde istatistiki açıdan ilişki bulunamamıştır. Şişmanlığın gelişiminde fazla kalori alınrmı nedeniyle PCHEnin karaciğerde uyanlıp yağ dokuda basküanması; PCHE, VLDL ve LDUnin artışına neden olmaktadır.
dc.description.abstract41 SUMMARY Plasma glucose. basal Insulin, cholesterol, triglyceride, phospho lipid, HDL-Cholesterol. LDL-Cholesterol, LDL-Cholesterol/HDLOıolesterol ratios and PCHE and EACHE levels of 30 underweight (BMI < 21). 30 normal weight (BM 21-26 ) and 30 overweight (BMI > 25) participants (aged 20-40.54 males.36 females) were evaluated. The values of underweight subjects were;AZ The values of overweight subjects were; The Triglyceride (p < 0.01). LDL-Cholesterol ( p < 0.01 ). PCHE (p< 0.001) values of under weight group were lower than those of normal weight group. The Triglyceride (p < 0.001). LDL-Cholesterol. (p < 0.001) and PCHE (p<0.001) values of obese group were lower and HDL-Cholesterol (p<0.01), EACHE (p < 0.001) values were higher than those of underwieght group. The Triglyceride (p < 0.01 ). LDL-Cholesterol. (p<0.001). PCHE (p < 0.01) values of overweight and obese group were lower and EACHE (p< 0.001) values were higher than those of normal weight group. By using correlation tests no sigjxiflcant difference was found among under weight normal weight and obese groups. It was concluded that In obesity, PCHE was stimulated in liver and inhibited in adipose tissue, and for these reason, PCHE, VLDL and LDL values were increased.en_US
dc.languageTurkish
dc.language.isotr
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.rightsAttribution 4.0 United Statestr_TR
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectBiyokimyatr_TR
dc.subjectBiochemistryen_US
dc.titleŞişman, zayıf ve normal kişilerde plazma kolinesteraz (PCHE) ve eritrosit içi kolinesteraz (EACHE) enzim aktiviteleri
dc.typemasterThesis
dc.date.updated2018-08-06
dc.contributor.departmentDiğer
dc.subject.ytmErythrocytes
dc.subject.ytmCholinesterases
dc.subject.ytmEnzyme activation
dc.subject.ytmHyperinsulinism
dc.subject.ytmHypertriglyceridemia
dc.subject.ytmObesity
dc.identifier.yokid30009
dc.publisher.instituteSağlık Bilimleri Enstitüsü
dc.publisher.universitySELÇUK ÜNİVERSİTESİ
dc.identifier.thesisid30009
dc.description.pages51
dc.publisher.disciplineDiğer


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

info:eu-repo/semantics/embargoedAccess
Except where otherwise noted, this item's license is described as info:eu-repo/semantics/embargoedAccess