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dc.contributor.advisorEntok, Emre
dc.contributor.authorŞimşek, Fikri Selçuk
dc.date.accessioned2020-12-29T11:14:10Z
dc.date.available2020-12-29T11:14:10Z
dc.date.submitted2011
dc.date.issued2018-08-06
dc.identifier.urihttps://acikbilim.yok.gov.tr/handle/20.500.12812/398144
dc.description.abstractBu çalışma primer odağı saptanamamış olgularda PET/CT'nin primer odağı tespit edebilme etkinliğini belirlemek amacıyla yapılmıştır. Primeri bilinmeyen karsinom tanısı alan ve bu tanı ile primer odağı saptamak amaçlı PET/CT çekilmesi planlanan 51 hasta çalışmaya dahil edildi. Artmış F?18 FDG odakları görsel ve semikantitatif analiz ile değerlendirildi. Ağırlıkları 48 ile 97 kg (ortalama 70,70±11,10) arasında değişmekteydi. Açlık kan şekeri düzeyleri 82 ile 149 mg/dl (ortalama 105,14±16,13) arasındaydı. Hesaplanan SUV max değerleri 0 ile 17,50 (ortalama 8,126±0,741) idi. Yaklaşık 20 dk süren görüntüleme hastalar tarafından iyi tolere edildi.. Histopatolojik olarak 23 hastada (%45,1) adenokarsinom, 16 hastada (%31,4) karsinom, 4 hastada (%7,8) malign epitelyal tümör, 3 hastada (%5,9) non small cell karsinom, 2 hastada (%3,9)squamoz hücreli karsinom, 1 hastada (%2)küçük hücreli karsinom, 1 hastada iğsi nitelikli karsinom ve 1 hastada renal hücreli karsinom bulguları vardı. Hastaların çekilen PET/BT' lerinde 13 hastada (%25,5) primer odak olabilecek lezyon saptanamazken, 15 hastada (%29,4) akciğer, 8 hastada (%15,7) kolon, 5 hastada pankreas (%9,8), 3 hastada karaciğer (%5,9) 2 hastada (%3,9) mide, 1 hastada (%2) plevra, 1 hastada (%2) uterus, 1 hastada böbrek (%2), 1 hastada (%2) nasofarenks ve 1 (%2) hastada peritonda primer lezyonla uyumlu olabilecek aktivite tutulumları tespit edildi. Sonuç olarak 38 hastada PET/CT ile primer odak saptanmıştır. PBK'larda primer odak tespitinde PET/CT'nin kullanımı umut vaat etmektedir.
dc.description.abstractThe aim of this study is to define primary focus detection efficiency of PET/CT in patients with carcinoma of unknown primary. Fifty one patients- who diagnosed with carcinoma of unknown primary and detected with PET/CT to define the primary focus- were included in this study.İncreased F-18 FDG foci were evaluated by visual and semiquantitative analysis. Weights of the patients were between 48 and 97 kg (average 70,70). Fasting blood glucose levels were between 82 and 149 mg/dl(average 105,14). SUV Max values calculated from 0 to 17,50 (average8,126) The patients tolarated well the 20 minutes study.In 23 patients (45,1) adenocarcinoma, 16 patients (31,4) carcinoma, 4 patients (%7,8) malignant epitelial tumor, 3 patients (%5,9) non small cell carcinoma, 2 patients (%3,9),squamous cell carcinoma, 1 patient (%2) small cell carcinoma,1 patient spindle cell carcinoma and 1 patient renal cell carcinoma were detected histopathologically. In 13 patients (%25,5) there was no evidence of primary focus, 15 patients (%29,4) lung, 8 patients (%15,7) colon, 5 patients (%9,8) pancreas, 3 patients (%5,9) liver, 2 patients (%3,9) stomach, 1 patient (%2) pleura, 1 patient (%2) uterus, 1 patient (%2) kidney, 1 patient (%2) nasopharnyx and 1 patient (%2) primary peritoneal lesion has detected as primary according to PET/CT results. As a result, PET/CT has been identified the primary focus in 38 patients. We think in patients with carcinoma of unknown primary to determine the primary focus PET/CT has a promising futureen_US
dc.languageTurkish
dc.language.isotr
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAttribution 4.0 United Statestr_TR
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectRadyoloji ve Nükleer Tıptr_TR
dc.subjectRadiology and Nuclear Medicineen_US
dc.titlePrimeri bilinmeyen karsinomlu hastalarda PET/CT`nin yeri
dc.title.alternativeThe importance of PET/CT in patients with carcinoma of unknown primary
dc.typedoctoralThesis
dc.date.updated2018-08-06
dc.contributor.departmentNükleer Tıp Anabilim Dalı
dc.subject.ytmPositron-emission tomography
dc.subject.ytmCarcinoma
dc.subject.ytmNeoplasms
dc.subject.ytmNeoplasm metastasis
dc.identifier.yokid419867
dc.publisher.instituteTıp Fakültesi
dc.publisher.universityESKİŞEHİR OSMANGAZİ ÜNİVERSİTESİ
dc.type.submedicineThesis
dc.identifier.thesisid297362
dc.description.pages83
dc.publisher.disciplineDiğer


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