Development of a wireless multichannel neural data transmission system

Abstract

Bu çalışmada, uyanık sıçanların sinirsel aksiyon-potansiyelinin iletilmesi için kompaktboyutlu kablosuz bir verici sistemi tasarlanıp, üretilmiştir. IEEE 802.11 teknolojisinikullanan sistem 16 ayrı mikro elektrottan alınan veriyi 6.4 Mbps hızında yollayabilmektedir.Deney hayvanlarına dolaşma imkanı veren bu sistem onların stres seviyesini düşürerek dahabaşarılı ölçümleri mümkün kılmaktadır.Ayrıca, çalışmanın ikinci kısmında silikon tabanlı mikro-işlenmiş mikroelektrotların tasarımıaçıklanmıştır. Yani tasarımlar sinirlerden 32 kanala kadar sinyallerin düşük gürültü ilealınmasına imkan vermektedir.

Implantable microelectrode arrays enable multichannel electrophysiological recordings fromthe mammalian brain during behavioral experiments. Wireless data transmission systemscombined with the microelectrode arrays and electrophysiology hardware allow thechronically-implanted subjects to freely move during the neural recording sessions. In thepresent study, a wireless neural data recording system is designed and implemented to collectdata from behaving rats. The system is based on an amplifier chip and a microcontroller with802.11 technology at the client side, and a PC equipped with LabVIEW software at the serverside. The system enables data throughput up to 6.4 Mbps for signals obtained from 16 channelmicroelectrode arrays with a sampling rate of 25 KHz per channel. Based on five recordingsessions each lasting 12.8 seconds, 9927.6 UDP packets ± 105.85 out of 10000 packets eachconsisting of 1024 bytes were received and recorded by the server. The present system offersa cost-effective and compact solution to perform multichannel in vivo electrophysiologicalrecordings from behaving rats. We also provide the design and 3D models of silicon-basedmicro-machined microelectrode arrays for extracellular neural signals from 8-32 channelsand evaluate the mechanical strength of these probes using simulations.