Aktinik keratozda tanıların klinik, histopatolojik ve dermatoskopik korelasyonu ve topikal tedavinin etkinliğinin immünohistokimyasal olarak değerlendirilmesi

Çayırlı, Mutlu

dc.contributor.advisor	Köse, Osman
dc.contributor.author	Çayırlı, Mutlu
dc.date.accessioned	2023-09-26T11:51:12Z
dc.date.available	2023-09-26T11:51:12Z
dc.date.submitted	2018-08-06
dc.date.issued	2010
dc.identifier.uri	https://acikbilim.yok.gov.tr/handle/20.500.12812/755294
dc.description.abstract	Klinik olarak aktinik keratoz tanısı konulan 44 hastada klinik, dermatoskopik ve histopatolojik tanılar ve bu tanısal yaklaşımlar arasındaki uyumluluk araştırılmıştır.Aynı zamanda kök hücre ve (p63,ck15,ck19)ve porliferasyon belirteçlerini (ki67 ve bcl-2) kullanarak immünohistokimyasal inceleme ile topikal diklofenak jel tedavisinin aktinik keratozdaki etkinliğide araştırılmıştır
dc.description.abstract	Total of 44 patients (66 lesions) clinically diagnosed to have actinic keratosis were enrolled in this study. Histopathological and dermatoscopic diagnosis of actinic keratosis and correlation of this diagnostic modalities was investigated. We also evaluated the efficacy of topical diclofenac sodium jel in actinic keratosis with immunohistochemical analysis using stem cell (p63, Ck-15, Ck-19) and proliferaton markers (Ki-67and Bcl-2).	en_US
dc.language	Turkish
dc.language.iso	tr
dc.rights	info:eu-repo/semantics/openAccess
dc.rights	Attribution 4.0 United States	tr_TR
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/
dc.subject	Dermatoloji	tr_TR
dc.subject	Dermatology	en_US
dc.title	Aktinik keratozda tanıların klinik, histopatolojik ve dermatoskopik korelasyonu ve topikal tedavinin etkinliğinin immünohistokimyasal olarak değerlendirilmesi
dc.title.alternative	The correlation of clinical, histopathological and dermatoscopic diagnosis in actinic keratosis and topical treatment efficacy with immunohistochemical evaluation
dc.type	doctoralThesis
dc.date.updated	2018-08-06
dc.contributor.department	Deri ve Zührevi Hast. Ana Bilim Dalı
dc.subject.ytm	Actins
dc.subject.ytm	Diclofenac
dc.subject.ytm	Keratosis
dc.subject.ytm	Diagnosis
dc.subject.ytm	Stem cells
dc.subject.ytm	Dermoscopy
dc.identifier.yokid	384271
dc.publisher.institute	Tıp Fakültesi
dc.publisher.university	GÜLHANE ASKERİ TIP AKADEMİSİ
dc.type.sub	medicineThesis
dc.identifier.thesisid	311660
dc.description.pages	91
dc.publisher.discipline	Diğer

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